ZIMIG OINTMENT 10 GM

ZIMIG OINTMENT 10 GM

By GLAXO SMITHKLINE PHARMACEUTICALS LIMITED

MRP 76.2
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About ZIMIG OINTMENT 10 GM

  • ZIMIG OINTMENT 10 GM is an antifungal medication used to treat various fungal infections, primarily affecting the skin and nails. It belongs to the allylamine class of antifungal drugs and works by inhibiting the growth of fungi.
  • ZIMIG OINTMENT 10 GM is available in various forms, including tablets, creams, and solutions, allowing for effective treatment of fungal infections both topically and systemically. It is commonly prescribed by healthcare professionals for conditions such as athlete's foot, ringworm, and fungal nail infections.

Uses of ZIMIG OINTMENT 10 GM

  • Helps in treating athlete's foot (tinea pedis)
  • Used in the treatment of ringworm infections (tinea corporis)
  • Effective against jock itch (tinea cruris)
  • Helps in curing fungal nail infections (onychomycosis)
  • Used to treat pityriasis versicolor, a fungal infection that causes discolored patches on the skin
  • Helps in alleviating symptoms associated with other fungal skin infections

How ZIMIG OINTMENT 10 GM Works

  • ZIMIG OINTMENT 10 GM works by inhibiting the enzyme squalene epoxidase, which is involved in the synthesis of ergosterol, an essential component of the fungal cell membrane. By disrupting the synthesis of ergosterol, ZIMIG OINTMENT 10 GM weakens the fungal cell membrane, leading to its death and eventual eradication of the fungal infection.
  • ZIMIG OINTMENT 10 GM exerts its antifungal effects by selectively inhibiting the enzyme squalene epoxidase, which is responsible for the conversion of squalene to lanosterol, a crucial step in the biosynthesis of ergosterol. Ergosterol is an essential component of the fungal cell membrane, providing structural integrity and stability. By inhibiting squalene epoxidase, ZIMIG OINTMENT 10 GM disrupts the production of ergosterol and causes the accumulation of toxic squalene precursors within the fungal cells. This disruption weakens the fungal cell membrane, leading to cell death and eventual clearance of the fungal infection. ZIMIG OINTMENT 10 GM exhibits fungicidal activity against a broad spectrum of fungi, including dermatophytes, yeasts, and molds. Its mechanism of action is specific to fungi and does not affect human cell membranes, making it an effective and safe treatment option for fungal infections.

Dosage of ZIMIG OINTMENT 10 GM Works

  • Dosage for children: The dosage of ZIMIG OINTMENT 10 GM for children may vary depending on the specific fungal infection and the child's age and weight. It is important to follow the prescribed dosage and duration of treatment recommended by a healthcare professional.
  • Dosage for adults: The standard dosage of ZIMIG OINTMENT 10 GM for adults is typically 250 mg once daily for most fungal infections. However, the dosage may vary based on the severity of the infection and individual factors. It is important to follow the instructions provided by a healthcare professional.

Side Effects Of ZIMIG OINTMENT 10 GM

Common Side Effects of ZIMIG OINTMENT 10 GM
  • Nausea
  • Diarrhea
  • Rash
  • Itching
  • Liver function abnormalities
  • Taste disturbances

How to Store ZIMIG OINTMENT 10 GM

  • Store ZIMIG OINTMENT 10 GM tablets at room temperature, away from moisture and heat.
  • ZIMIG OINTMENT 10 GM creams and solutions should be stored according to the instructions provided on the packaging.

Frequently asked questions about ZIMIG OINTMENT 10 GM

The safety of ZIMIG OINTMENT 10 GM during pregnancy is not well established. It is generally recommended to avoid ZIMIG OINTMENT 10 GM use during pregnancy unless the benefits outweigh the potential risks.

ZIMIG OINTMENT 10 GM can be used for scalp fungal infections. It is available in both oral and topical forms, but oral administration is usually more effective for scalp infections.

ZIMIG OINTMENT 10 GM has the potential for drug interactions with certain medications, such as cyclosporine, cimetidine, rifampin, and some antidepressants. It's important to consult with a healthcare professional or pharmacist to check for any specific drug interactions.

Common side effects of ZIMIG OINTMENT 10 GM may include gastrointestinal disturbances (such as nausea, diarrhea, or stomach pain), headache, taste disturbances, and skin rashes. Serious side effects are rare but can include liver problems, blood disorders, and allergic reactions.

The duration for ZIMIG OINTMENT 10 GM to work depends on the type and severity of the fungal infection. In general, it may take several weeks to a few months of continuous treatment to see improvement.

Although rare, ZIMIG OINTMENT 10 GM has been associated with cases of liver damage. It is important to monitor liver function during ZIMIG OINTMENT 10 GM treatment, especially in patients with pre-existing liver conditions or a history of liver disease.

ZIMIG OINTMENT 10 GM can generally be used safely in elderly patients. However, caution should be exercised, and regular monitoring of liver function is recommended due to the increased risk of liver-related side effects in this population.

ZIMIG OINTMENT 10 GM can be used to treat fungal infections in children. However, the appropriate dosage and duration of treatment may vary based on the child's age and weight. It is best to consult a healthcare professional for proper guidance and dosage recommendations for children.

References related to ZIMIG OINTMENT 10 GM

  1. Terbinafine (Oral Route) Side Effects - Mayo Clinic. (2023). Retrieved June 27, 2023, from Mayoclinic.org website: https://www.mayoclinic.org/drugs-supplements/terbinafine-oral-route/side-effects/drg-20066265?p=1#:~:text=Terbinafine%20belongs%20to%20the%20group,only%20with%20your%20doctor's%20prescription. image
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Reviewed on 20 May 2023

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