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PANGRAF 1MG CAPSULE 10'S
By MANKIND PHARMA LIMITED
MRP
₹
454.94
₹386.7
15 % OFF
₹38.67 Only /
CAPSULE
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Composition
Product Details
About PANGRAF 1MG CAPSULE 10'S
PANGRAF 1MG CAPSULE 10'S is an immunosuppressive medication that is primarily used to prevent organ rejection in individuals who have undergone organ transplantation. It belongs to the class of medications known as calcineurin inhibitors. PANGRAF 1MG CAPSULE 10'S helps in suppressing the immune system to prevent it from attacking the transplanted organ, thereby increasing the chances of successful organ transplantation and long-term graft survival.
Uses of PANGRAF 1MG CAPSULE 10'S
- Helps in preventing organ rejection in individuals who have received a kidney, liver, heart, or lung transplant.
- Is used in combination with other immunosuppressive medications to maintain the function and viability of the transplanted organ.
- Is used in the treatment of certain autoimmune skin conditions such as atopic dermatitis, eczema, and psoriasis.
- Is used off-label for the management of other immune-mediated conditions such as rheumatoid arthritis and ulcerative colitis.
- Is used in the treatment of severe refractory uveitis, a condition characterized by inflammation of the eye's uvea.
- Is used topically for the treatment of moderate to severe atopic dermatitis in patients who have not responded well to other treatments.
- Is used in combination with other medications to treat certain types of inflammatory bowel disease, such as Crohn's disease.
How PANGRAF 1MG CAPSULE 10'S Works
- PANGRAF 1MG CAPSULE 10'S works by inhibiting the activity of calcineurin, an enzyme involved in the activation of T cells. By suppressing T-cell activation, it helps in reducing the immune response and preventing organ rejection in transplant recipients.
- PANGRAF 1MG CAPSULE 10'S exerts its therapeutic effects by selectively inhibiting the activity of calcineurin, an enzyme responsible for the activation of T cells. T cells play a crucial role in the immune response, including the rejection of transplanted organs. By inhibiting calcineurin, PANGRAF 1MG CAPSULE 10'S blocks the signaling pathway that leads to the production of cytokines and other molecules involved in the immune response. This effectively suppresses the immune system, reducing the activity of T cells and preventing them from attacking the transplanted organ. In the case of topical use, PANGRAF 1MG CAPSULE 10'S penetrates the skin and inhibits the activation of immune cells in the skin, reducing inflammation and symptoms associated with conditions like atopic dermatitis. However, it is important to note that the precise mechanism of action of PANGRAF 1MG CAPSULE 10'S in skin disorders is not fully understood.
Side Effects of PANGRAF 1MG CAPSULE 10'S
- Diarrhea
- High blood pressure
- Kidney damage
- Headache
- Tremor
- Increased risk of certain types of cancer (with long-term use)
- Skin reactions (topical use)
Dosage of PANGRAF 1MG CAPSULE 10'S
- Dosage for children: The specific dosage of PANGRAF 1MG CAPSULE 10'S for children undergoing organ transplantation or receiving treatment for skin conditions should be determined by a healthcare professional based on the child's age, weight, and the specific condition being treated. The dosage may be adjusted over time to achieve the desired therapeutic effect while minimizing side effects.
- Dosage for adults: The recommended dosage of PANGRAF 1MG CAPSULE 10'S varies depending on the type of organ transplant or the specific skin condition being treated. The dosage may be adjusted based on individual factors such as the patient's age, weight, kidney function, and response to therapy. It is important to follow the prescribed dosage and consult a healthcare professional for guidance.
How to store PANGRAF 1MG CAPSULE 10'S?
- PANGRAF 1MG CAPSULE 10'S should be stored at room temperature, away from heat and direct sunlight. It is important to keep it in its original packaging and out of reach of children. Follow any specific storage instructions provided by the manufacturer.
FAQs
Is PANGRAF 1MG CAPSULE 10'S safe for long-term use?
Yes, PANGRAF 1MG CAPSULE 10'S can be used safely for long-term treatment under the supervision of a healthcare professional. Regular monitoring is essential to assess its effectiveness and manage any potential side effects.
Can PANGRAF 1MG CAPSULE 10'S be used during pregnancy?
The use of PANGRAF 1MG CAPSULE 10'S during pregnancy should be discussed with a healthcare professional. They can evaluate the potential risks and benefits and make an informed decision based on the individual's specific situation.
What are the common side effects of PANGRAF 1MG CAPSULE 10'S?
Common side effects of PANGRAF 1MG CAPSULE 10'S include increased susceptibility to infections, gastrointestinal symptoms (such as nausea and diarrhea), high blood pressure, headache, tremor, and kidney damage. Regular monitoring is important to detect and manage these side effects.
Can PANGRAF 1MG CAPSULE 10'S be used in children?
Yes, PANGRAF 1MG CAPSULE 10'S can be used in children for certain conditions, such as organ transplantation or specific skin disorders. The dosage and treatment duration should be determined by a healthcare professional based on the child's specific needs and individual factors.
How does PANGRAF 1MG CAPSULE 10'S interact with other medications?
PANGRAF 1MG CAPSULE 10'S can interact with certain medications, including other immunosuppressants and drugs metabolized by the liver. It is important to inform the healthcare professional about all medications being taken to avoid potential interactions. They can provide guidance on any necessary adjustments or precautions.
Can PANGRAF 1MG CAPSULE 10'S be used topically for skin conditions?
Yes, PANGRAF 1MG CAPSULE 10'S is available as a topical formulation for the treatment of certain skin conditions, such as atopic dermatitis. It should be used as directed by the healthcare professional and for the recommended duration. Regular follow-up is important to assess its effectiveness and manage any potential side effects.
Are there any dietary restrictions while taking PANGRAF 1MG CAPSULE 10'S?
While taking PANGRAF 1MG CAPSULE 10'S, certain dietary restrictions may apply. For example, it is important to avoid consuming grapefruit and grapefruit juice, as they can interfere with the metabolism of PANGRAF 1MG CAPSULE 10'S and affect its effectiveness. It is advisable to follow any dietary recommendations provided by the healthcare professional or pharmacist.
What types of organ transplants is PANGRAF 1MG CAPSULE 10'S used for?
PANGRAF 1MG CAPSULE 10'S is primarily used for kidney, liver, heart, and lung transplants. It is effective in preventing organ rejection and ensuring the long-term viability of the transplanted organs. The specific suitability and dosing of PANGRAF 1MG CAPSULE 10'S may vary depending on the type of organ transplant and individual factors. A healthcare professional can provide detailed information and guidance specific to each case.
Are there any long-term side effects associated with Pangraf 1mg Capsule?
Long-term use may increase the risk of infections and certain cancers due to immune system suppression. Regular medical check-ups are essential to monitor for these potential risks.
References
Ratings & Review
Service and prize is good
Bhavin Shah
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Reviewed on 13-04-2024
(5/5)
Gotri Medkart Pharmacy providing generic medicines & other products with affordable price with better service.
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Reviewed on 11-01-2024
(5/5)
Best medicines, Timing and behaviour is very good for human beings
Gyan Rathore
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Reviewed on 07-08-2023
(5/5)
Best and cheapest medicine.
Shubham Jain
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Reviewed on 23-11-2022
(5/5)
Very good customer approach
Ketan Sarkar
•
Reviewed on 20-01-2024
(5/5)
Marketer / Manufacturer Details
MANKIND PHARMA LIMITED
Country of Origin -
India
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