MIKASTAR 250MG INJECTION 2 ML
By MANKIND PHARMA LIMITED
Contains: AMIKACIN 250 MG
About MIKASTAR 250MG INJECTION 2 ML
- MIKASTAR 250MG INJECTION 2 ML is a powerful antibiotic medication commonly used in the treatment of severe bacterial infections. It belongs to the class of drugs known as aminoglycosides and is particularly effective against Gram-negative bacteria. MIKASTAR 250MG INJECTION 2 ML works by inhibiting the production of proteins in the bacteria, thus preventing their growth and ultimately killing them. This antibiotic is often reserved for infections that are resistant to other antibiotics or for patients who are unable to tolerate alternative medications.
- Due to its potent nature, MIKASTAR 250MG INJECTION 2 ML is primarily administered intravenously or intramuscularly, ensuring rapid and effective distribution throughout the body. The dosage and duration of treatment with MIKASTAR 250MG INJECTION 2 ML are carefully determined by healthcare professionals based on factors such as the type of infection, the patient's age, weight, and kidney function. Regular monitoring of kidney function and blood levels of the medication is crucial to prevent potential toxicity.
- While MIKASTAR 250MG INJECTION 2 ML can be highly effective in combating bacterial infections, it is not without risks. The most common side effects include nephrotoxicity (kidney damage) and ototoxicity (hearing and balance problems), particularly with prolonged or high-dose usage. Therefore, close monitoring of patients receiving MIKASTAR 250MG INJECTION 2 ML is essential to detect any potential adverse effects early on. Despite its associated risks, MIKASTAR 250MG INJECTION 2 ML remains a vital and effective treatment option for serious infections when other antibiotics have failed or are ineffective.
Uses of MIKASTAR 250MG INJECTION 2 ML
- Used to treat severe bacterial infections
- Prescribe for Combination therapy for multidrug-resistant tuberculosis (MDR-TB)
- Prescribe for Neonatal sepsis
Benefits of MIKASTAR 250MG INJECTION 2 ML
How MIKASTAR 250MG INJECTION 2 ML Works
- MIKASTAR 250MG INJECTION 2 ML works by inhibiting the production of proteins in bacteria, ultimately leading to their death.
- MIKASTAR 250MG INJECTION 2 ML is an antibiotic belonging to the aminoglycoside class.
- It inhibits bacterial protein synthesis by binding to the bacterial ribosome.
- By binding to the ribosome, MIKASTAR 250MG INJECTION 2 ML disrupts the reading and translation of the bacterial genetic code.
- This disruption prevents the formation of functional proteins necessary for bacterial growth and survival.
- MIKASTAR 250MG INJECTION 2 ML forms irreversible complexes with the bacterial ribosome, leading to a prolonged inhibition of protein synthesis.
- It exhibits bactericidal activity, actively killing the bacteria rather than merely inhibiting their growth.
- MIKASTAR 250MG INJECTION 2 ML is effective against a broad spectrum of bacteria, particularly Gram-negative bacteria like Pseudomonas aeruginosa, Escherichia coli, and Klebsiella pneumoniae.
- It can penetrate the outer membranes of resistant bacteria, reaching intracellular targets.
Dosage of MIKASTAR 250MG INJECTION 2 ML Works
- For Children:
- Neonates (up to 1 month old):
- Loading dose: 15 mg/kg
- Maintenance dose: 7.5 mg/kg every 12 hours
- Infants and Children (1 month to 12 years old):
- Loading dose: 15 mg/kg
- Maintenance dose: 7.5 mg/kg every 12 hours
- Dosage for Adults:
- For Adult:
- Loading dose: 15 mg/kg
- Maintenance dose: 7.5 mg/kg to 15 mg/kg every 12 hours
- Severe Infections or Infections Caused by Pseudomonas aeruginosa:
- Loading dose: 15 mg/kg to 25 mg/kg
- Maintenance dose: 15 mg/kg to 25 mg/kg every 8 hours
Side Effects Of MIKASTAR 250MG INJECTION 2 ML
- Kidney damage (nephrotoxicity)
- Hearing and balance problems (ototoxicity)
- Allergic reactions
- Neurotoxicity
- Gastrointestinal disturbances
How to Store MIKASTAR 250MG INJECTION 2 ML
- MIKASTAR 250MG INJECTION 2 ML should be stored at controlled room temperature, typically between 20°C to 25°C (68°F to 77°F).
- Avoid exposing MIKASTAR 250MG INJECTION 2 ML to extreme heat or cold, so it should not be refrigerated or frozen.
- Protect MIKASTAR 250MG INJECTION 2 ML vials or ampules from light by keeping them in their original packaging or in a container that shields them from direct sunlight or bright artificial light.
- Store MIKASTAR 250MG INJECTION 2 ML in a dry environment to prevent moisture absorption. Avoid storing it in humid areas such as bathrooms or kitchen sinks.
Frequently asked questions about MIKASTAR 250MG INJECTION 2 ML
MIKASTAR 250MG INJECTION 2 ML is used to treat severe bacterial infections, particularly those caused by Gram-negative bacteria.
MIKASTAR 250MG INJECTION 2 ML is typically administered through intravenous (IV) or intramuscular (IM) routes. The specific method of administration and dosage will depend on factors such as the patient's age, weight, renal function, and the severity of the infection.
Common side effects of MIKASTAR 250MG INJECTION 2 ML include nephrotoxicity (kidney damage), ototoxicity (hearing and balance problems), gastrointestinal disturbances (nausea, vomiting, diarrhea), and allergic reactions.
The use of MIKASTAR 250MG INJECTION 2 ML during pregnancy should be done with caution and under the guidance of a healthcare professional. Its use during breastfeeding should be discussed with a doctor as it may pass into breast milk.
MIKASTAR 250MG INJECTION 2 ML may interact with certain medications, including other antibiotics, diuretics, and neuromuscular blocking agents. It is important to inform the healthcare professional about all medications, supplements, or herbal products being taken to avoid potential drug interactions.
Precautions while using MIKASTAR 250MG INJECTION 2 ML include closely monitoring kidney function and hearing status, regular blood tests to assess medication levels, and completing the full course of treatment as prescribed, even if symptoms improve. Consulting with a healthcare professional or pharmacist for specific guidance is important.
References related to MIKASTAR 250MG INJECTION 2 ML
- CDSCO. (2023). Retrieved May 31, 2023, from Cdscoonline.gov.in website: https://cdscoonline.gov.in/CDSCO/Drugs
- https://www.facebook.com/Drugscom. (2022). Amikacin Use During Pregnancy. Retrieved May 31, 2023, from Drugs.com website: https://www.drugs.com/pregnancy/amikacin.html
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