BRIMONIX BR DROPS 5 ML

How BRIMONIX BR DROPS 5 ML Works

• BRIMONIX BR eye drops 5 ML is a combination medication designed to manage elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. It combines the effects of brimonidine tartrate and brinzolamide, each working through different mechanisms to lower IOP and protect the optic nerve.
• Brimonidine tartrate is an alpha-2 adrenergic agonist. It works by reducing the production of aqueous humor (the fluid in the eye) and increasing the outflow of aqueous humor from the eye. By stimulating alpha-2 adrenergic receptors in the ciliary body, brimonidine decreases the rate at which aqueous humor is produced. Additionally, it enhances the uveoscleral outflow, a secondary drainage pathway for aqueous humor. This dual action helps lower the overall pressure inside the eye.
• Brinzolamide is a carbonic anhydrase inhibitor. It reduces IOP by decreasing the production of aqueous humor. Carbonic anhydrase is an enzyme present in the ciliary processes of the eye, which is involved in the secretion of aqueous humor. Brinzolamide inhibits this enzyme, thereby slowing down the formation of bicarbonate ions. This reduction in bicarbonate ions leads to decreased fluid transport and, consequently, less aqueous humor production. Brinzolamide selectively targets carbonic anhydrase II, which is the isoenzyme primarily found in the eye.
• The synergistic effect of brimonidine and brinzolamide provides a more effective reduction in IOP compared to either medication used alone. By targeting both aqueous humor production and outflow, BRIMONIX BR offers comprehensive pressure control. This is crucial for preventing damage to the optic nerve, which is the primary cause of vision loss in glaucoma.
• In summary, BRIMONIX BR eye drops work by a dual mechanism: brimonidine reduces aqueous humor production and increases outflow, while brinzolamide inhibits carbonic anhydrase to decrease aqueous humor production. This combination effectively lowers intraocular pressure, helping to manage glaucoma and ocular hypertension and protect vision.

Common side effects of Brimonix BR eye drops may include: * Burning or stinging sensation in the eye * Blurred vision * Dry eye * Itching of the eye * Redness of the eye * Foreign body sensation * Tearing * Headache * Drowsiness * Dry mouth Less common side effects may include: * Eye pain * Allergic reactions (eye lid swelling, itching) * High Blood Pressure * Dizziness * Fainting * Irregular Heartbeat * Depression Rare side effects: * Severe allergic reactions * Low blood pressure This is not an exhaustive list. If you experience any unusual or severe side effects, stop using Brimonix BR and consult your doctor immediately.

• If you miss a dose of Brimonix BR eye drops, use it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep BRIMONIX BR DROPS 5ML away from the reach of children and pets.
• Store BRIMONIX BR DROPS 5ML at room temperature.

• **Wash Your Hands:** Always wash your hands thoroughly with soap and water before administering BRIMONIX BR DROPS 5 ML to prevent contamination of the eye and the medication.
• **Proper Instillation Technique:** Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye and gently squeeze out the prescribed number of drops. Avoid touching the dropper tip to your eye or any other surface to prevent contamination.
• **Avoid Contact Lenses:** If you wear contact lenses, remove them before using BRIMONIX BR DROPS 5 ML. You can reinsert them 15 minutes after applying the drops, unless your doctor advises otherwise. Contact lenses can absorb the medication, reducing its effectiveness and potentially causing irritation.
• **Consistent Timing:** Administer BRIMONIX BR DROPS 5 ML at the same time(s) each day as prescribed by your doctor. This helps maintain a consistent level of medication in your system for optimal effectiveness in managing glaucoma or ocular hypertension. Setting a reminder can be helpful to ensure adherence.
• **Storage Instructions:** Store BRIMONIX BR DROPS 5 ML at room temperature, away from direct sunlight and heat. Keep the bottle tightly closed when not in use. Do not use the drops if the solution changes color or contains particles. Discard the bottle after the expiry date or one month after opening, even if there is solution remaining. Expired or contaminated eye drops can lead to infection or reduced effectiveness.
• **Monitor for Side Effects:** Be aware of potential side effects such as blurred vision, eye irritation, dry mouth, drowsiness, or changes in blood pressure. If you experience any severe or persistent side effects, contact your doctor immediately. Do not drive or operate heavy machinery until you know how BRIMONIX BR DROPS 5 ML affects you.
• **Inform Your Doctor:** Inform your doctor about all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with BRIMONIX BR DROPS 5 ML. Also, inform your doctor about any other medical conditions you have, especially heart conditions, low blood pressure, or kidney problems.
• **Do not use if seal is broken:** Check the seal of the product before using it, do not use if it's broken. Always keep medicine in the same container to avoid contamination.
• **Consult Doctor before using other medicines:** If you are using other eye drops then consult doctor before using it.

• There are no known food interactions with BRIMONIX BR DROPS 5 ML. It can be administered regardless of food intake.