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APREZO 30MG TABLET 10'S
By GLENMARK PHARMACEUTICALS LIMITED
MRP
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₹276.25
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Product Details
About APREZO 30MG TABLET 10'S
APREZO 30MG TABLET 10'S is primarily used for the treatment of certain inflammatory conditions, specifically psoriasis and psoriatic arthritis. Here is an overview of Apremilast:,APREZO 30MG TABLET 10'S works by inhibiting the enzyme phosphodiesterase-4 (PDE4). This helps to modulate the overactive immune response associated with psoriasis and psoriatic arthritis. APREZO 30MG TABLET 10'S is approved for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy. It is also indicated for the treatment of active psoriatic arthritis in adult patients, either as monotherapy or in combination with other disease-modifying antirheumatic drugs (DMARDS).,APREZO 30MG TABLET 10'S has been shown to significantly improve the signs and symptoms of plaque psoriasis, including reducing the redness, scaling, and thickness of skin lesions. It can lead to a reduction in psoriasis severity and improve the quality of life for patients with this chronic skin condition.
Uses of APREZO 30MG TABLET 10'S
- Effectively treats moderate to severe plaque psoriasis, reducing the redness, scaling, and thickness of skin lesions.
- Improves the signs and symptoms of psoriatic arthritis, including joint pain, swelling, and tenderness.
- Can be used for psoriatic arthritis treatment.
- Helps improve physical function and inhibit the progression of structural damage associated with psoriatic arthritis.
How APREZO 30MG TABLET 10'S Works
- APREZO 30MG TABLET 10'S works by targeting a specific enzyme called phosphodiesterase-4 (PDE4), which is found in various cells of the body, including immune cells. Here is an explanation of how APREZO 30MG TABLET 10'S works:
- Inhibition of PDE4: APREZO 30MG TABLET 10'S acts as a selective inhibitor of PDE4. By inhibiting PDE4, it prevents the breakdown of cyclic adenosine monophosphate (CAMP), an important signaling molecule within cells.
- Modulation of Inflammatory Response: By inhibiting PDE4 and increasing CAMP levels, APREZO 30MG TABLET 10'S helps regulate the immune system and modulate the inflammatory response. It reduces the production of certain pro-inflammatory cytokines (chemical messengers) such as tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-17 (IL-17), and interleukin-23 (IL-23).
- Anti-Inflammatory Effects: APREZO 30MG TABLET 10'S ability to inhibit the production of pro-inflammatory cytokines helps to reduce the overall inflammation in the body. This can be beneficial in conditions such as psoriasis and psoriatic arthritis, where excessive inflammation plays a role in the development of symptoms.
- Impact on Immune Cells: APREZO 30MG TABLET 10'S affects various immune cells, including T cells, B cells, and dendritic cells. By modulating the activity of these immune cells, it helps to regulate the immune response and reduce inflammation.
Side Effects of APREZO 30MG TABLET 10'S
- Diarrhea
- Nausea
- Headache
- Upper respiratory tract infections
- Decreased appetite
- Fatigue
- Weight loss
- Depression or worsening of pre-existing depression
- Suicidal thoughts or behavior (rare but serious)
Dosage of APREZO 30MG TABLET 10'S
- Adults: For the treatment of moderate to severe plaque psoriasis: The typical starting dosage is 30 mg taken orally twice daily for the first 5 days, followed by a maintenance dosage of 30 mg taken orally twice daily thereafter.
- For the treatment of active psoriatic arthritis: The recommended dosage is 30 mg taken orally twice daily.
- Pediatrics (17 years and younger): APREZO 30MG TABLET 10'S is generally not recommended for use in pediatric patients. Safety and efficacy in this age group have not been well-established.
- Elderly: The dosage of APREZO 30MG TABLET 10'S for elderly patients (65 years and older) is typically the same as that for adults. However, individualized dosage adjustments may be necessary based on the patient's overall health, renal function, and other factors. It is important to consult with a healthcare professional for appropriate dosage recommendations.
How to store APREZO 30MG TABLET 10'S?
- Store Apremilast at room temperature, typically between 20°C to 25°C (68°F to 77°F).
- Keep the medication in its original container or packaging to protect it from light.
- Store it in a dry place, away from areas with high humidity, such as bathrooms.
FAQs
What is APREZO 30MG TABLET 10'S?
APREZO 30MG TABLET 10'S is an oral medication used for the treatment of certain inflammatory conditions, such as psoriasis and psoriatic arthritis.
What conditions is APREZO 30MG TABLET 10'S used to treat?
APREZO 30MG TABLET 10'S is used to treat moderate to severe plaque psoriasis and active psoriatic arthritis in adult patients.
How is APREZO 30MG TABLET 10'S administered?
APREZO 30MG TABLET 10'S is administered orally as a tablet, usually taken twice daily or as prescribed by a healthcare professional.
Are there any specific precautions or warnings associated with APREZO 30MG TABLET 10'S?
Precautions and warnings associated with APREZO 30MG TABLET 10'S include the risk of depression, suicidal thoughts, and possible drug interactions. It is important to discuss these factors with a healthcare professional.
Can APREZO 30MG TABLET 10'S be used during pregnancy or while breastfeeding?
The use of APREZO 30MG TABLET 10'S during pregnancy or breastfeeding should be discussed with a healthcare professional, considering the potential risks and benefits.
Are there any known drug interactions with APREZO 30MG TABLET 10'S?
APREZO 30MG TABLET 10'S may interact with certain medications, so it is important to inform healthcare professionals about all medications being taken.
How long does it take for APREZO 30MG TABLET 10'S to start working?
The onset of action for APREZO 30MG TABLET 10'S may vary among individuals and the specific condition being treated. It is best to consult a healthcare professional for an estimation of the expected time frame.
What should I do if I miss a dose of APREZO 30MG TABLET 10'S?
If a dose of APREZO 30MG TABLET 10'S is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose.
What are the common side effects of Aprezo 30mg Tablet?
Common side effects include diarrhea, nausea, headache, upper respiratory tract infections, decreased appetite, fatigue, weight loss, and, rarely, depression or suicidal thoughts.
References
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Reviewed on 10-03-2024
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Reviewed on 08-02-2024
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Reviewed on 15-05-2023
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Reviewed on 19-01-2024
(5/5)
Marketer / Manufacturer Details
GLENMARK PHARMACEUTICALS LIMITED
Country of Origin -
India
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