APREZO 20MG TABLET 4'S
By GLENMARK PHARMACEUTICALS LIMITED
Contains: APREMILAST 20 MG
Product Summary
| Offer Price | ₹ 97.75 |
|---|---|
| Your Savings | ₹ 17.25 (15% on MRP) |
About APREZO 20MG TABLET 4'S
- APREZO 20MG TABLET 4'S is primarily used for the treatment of certain inflammatory conditions, specifically psoriasis and psoriatic arthritis. Here is an overview of Apremilast:
- APREZO 20MG TABLET 4'S works by inhibiting the enzyme phosphodiesterase-4 (PDE4). This helps to modulate the overactive immune response associated with psoriasis and psoriatic arthritis. APREZO 20MG TABLET 4'S is approved for the treatment of moderate to severe plaque psoriasis in adult patients who are candidates for systemic therapy. It is also indicated for the treatment of active psoriatic arthritis in adult patients, either as monotherapy or in combination with other disease-modifying antirheumatic drugs (DMARDs).
- APREZO 20MG TABLET 4'S has been shown to significantly improve the signs and symptoms of plaque psoriasis, including reducing the redness, scaling, and thickness of skin lesions. It can lead to a reduction in psoriasis severity and improve the quality of life for patients with this chronic skin condition.
Uses of APREZO 20MG TABLET 4'S
- Effectively treats moderate to severe plaque psoriasis, reducing the redness, scaling, and thickness of skin lesions.
- Improves the signs and symptoms of psoriatic arthritis, including joint pain, swelling, and tenderness.
- Can be used for psoriatic arthritis treatment.
- Helps improve physical function and inhibit the progression of structural damage associated with psoriatic arthritis.
How APREZO 20MG TABLET 4'S Works
- APREZO 20MG TABLET 4'S works by targeting a specific enzyme called phosphodiesterase-4 (PDE4), which is found in various cells of the body, including immune cells. Here is an explanation of how APREZO 20MG TABLET 4'S works:
- Inhibition of PDE4: APREZO 20MG TABLET 4'S acts as a selective inhibitor of PDE4. By inhibiting PDE4, it prevents the breakdown of cyclic adenosine monophosphate (cAMP), an important signaling molecule within cells.
- Modulation of Inflammatory Response: By inhibiting PDE4 and increasing cAMP levels, APREZO 20MG TABLET 4'S helps regulate the immune system and modulate the inflammatory response. It reduces the production of certain pro-inflammatory cytokines (chemical messengers) such as tumor necrosis factor-alpha (TNF-alpha), interferon-gamma (IFN-gamma), interleukin-17 (IL-17), and interleukin-23 (IL-23).
- Anti-Inflammatory Effects: APREZO 20MG TABLET 4'S ability to inhibit the production of pro-inflammatory cytokines helps to reduce the overall inflammation in the body. This can be beneficial in conditions such as psoriasis and psoriatic arthritis, where excessive inflammation plays a role in the development of symptoms.
- Impact on Immune Cells: APREZO 20MG TABLET 4'S affects various immune cells, including T cells, B cells, and dendritic cells. By modulating the activity of these immune cells, it helps to regulate the immune response and reduce inflammation.
Dosage of APREZO 20MG TABLET 4'S Works
- Adults: For the treatment of moderate to severe plaque psoriasis: The typical starting dosage is 30 mg taken orally twice daily for the first 5 days, followed by a maintenance dosage of 30 mg taken orally twice daily thereafter.
- For the treatment of active psoriatic arthritis: The recommended dosage is 30 mg taken orally twice daily.
- Pediatrics (17 years and younger): APREZO 20MG TABLET 4'S is generally not recommended for use in pediatric patients. Safety and efficacy in this age group have not been well-established.
- Elderly: The dosage of APREZO 20MG TABLET 4'S for elderly patients (65 years and older) is typically the same as that for adults. However, individualized dosage adjustments may be necessary based on the patient's overall health, renal function, and other factors. It is important to consult with a healthcare professional for appropriate dosage recommendations.
Side Effects Of APREZO 20MG TABLET 4'S
- Diarrhea
- Nausea
- Headache
- Upper respiratory tract infections
- Decreased appetite
- Fatigue
- Weight loss
- Depression or worsening of pre-existing depression
- Suicidal thoughts or behavior (rare but serious)
How to Store APREZO 20MG TABLET 4'S
- Store Apremilast at room temperature, typically between 20°C to 25°C (68°F to 77°F).
- Keep the medication in its original container or packaging to protect it from light.
- Store it in a dry place, away from areas with high humidity, such as bathrooms.
Frequently asked questions about APREZO 20MG TABLET 4'S
APREZO 20MG TABLET 4'S is an oral medication used for the treatment of certain inflammatory conditions, such as psoriasis and psoriatic arthritis.
APREZO 20MG TABLET 4'S is used to treat moderate to severe plaque psoriasis and active psoriatic arthritis in adult patients.
APREZO 20MG TABLET 4'S is administered orally as a tablet, usually taken twice daily or as prescribed by a healthcare professional.
Precautions and warnings associated with APREZO 20MG TABLET 4'S include the risk of depression, suicidal thoughts, and possible drug interactions. It is important to discuss these factors with a healthcare professional.
The use of APREZO 20MG TABLET 4'S during pregnancy or breastfeeding should be discussed with a healthcare professional, considering the potential risks and benefits.
APREZO 20MG TABLET 4'S may interact with certain medications, so it is important to inform healthcare professionals about all medications being taken.
The onset of action for APREZO 20MG TABLET 4'S may vary among individuals and the specific condition being treated. It is best to consult a healthcare professional for an estimation of the expected time frame.
If a dose of APREZO 20MG TABLET 4'S is missed, it should be taken as soon as remembered, unless it is close to the time for the next scheduled dose.
References related to APREZO 20MG TABLET 4'S
- Medscape. Apremilast. [Accessed 02 Apr. 2019] (online) Available from
- National Drug Monograph. Apermilast; 2015. [Accessed 02 Apr. 2019] (online) Available from:
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