AMITONE 25MG TABLET 10'S
By INTAS PHARMACEUTICALS LIMITED
Contains: AMITRIPTYLINE 25 MG
About AMITONE 25MG TABLET 10'S
- AMITONE 25MG TABLET 10'S is a medication that belongs to the class of drugs known as tricyclic antidepressants (TCAs). It is primarily used to treat major depressive disorder, but it can also be prescribed for other conditions such as chronic pain, migraines, and certain sleep disorders. AMITONE 25MG TABLET 10'S works by affecting the balance of certain chemicals in the brain, including serotonin.
- It also helps to increase the levels of serotonin in the brain by inhibiting their reuptake, leading to improved mood and alleviation of depressive symptoms. Additionally, AMITONE 25MG TABLET 10'S has sedative properties, which can be beneficial for individuals with sleep disorders.
Uses of AMITONE 25MG TABLET 10'S
- Treats depression
- Reduces Chronic Pain
- Reduces frequency of Migraine Headaches
- Manages anxiety
How AMITONE 25MG TABLET 10'S Works
- AMITONE 25MG TABLET 10'S works by affecting the levels of certain neurotransmitters in the brain. It is classified as a tricyclic antidepressant (TCA) due to its chemical structure.
- AMITONE 25MG TABLET 10'S blocks the reuptake of serotonin and Norepinephrinen in the brain. Normally, after these neurotransmitters are released, they are reabsorbed by the neurons that released them. By inhibiting their reuptake, AMITONE 25MG TABLET 10'S allows serotonin and Norepinephrinen to remain in the synaptic space for a longer duration. This helps to increase their concentration and enhances their effects on mood regulation.
- Anticholinergic Effects: AMITONE 25MG TABLET 10'S has anticholinergic properties, which means it blocks the activity of acetylcholine, another neurotransmitter. This action can lead to side effects such as dry mouth, blurred vision, and constipation. The anticholinergic effects of amitriptyline are also responsible for its sedative properties.
- Alpha-Adrenergic Blockade: AMITONE 25MG TABLET 10'S blocks certain receptors called alpha-adrenergic receptors. This action can lead to a decrease in certain symptoms associated with depression, such as anxiety, agitation, and insomnia.
Dosage of AMITONE 25MG TABLET 10'S Works
- Adults:
- Depression: The typical starting dose for adults is 75-150 mg per day, divided into multiple doses. This can be adjusted based on the individual's response and tolerance, with the maximum dose usually not exceeding 300 mg per day.
- Chronic Pain: For pain management, lower doses of AMITONE 25MG TABLET 10'S are often used. The starting dose can range from 10-25 mg at bedtime, gradually increasing if needed.
- Older Adults (Elderly):
- Older adults are generally more susceptible to the side effects of amitriptyline due to age-related changes in metabolism and increased sensitivity. Therefore, lower starting doses are often recommended, usually starting at 10-25 mg at bedtime. The dosage may be adjusted cautiously and closely monitored.
Side Effects Of AMITONE 25MG TABLET 10'S
- Drowsiness
- Dry Mouth
- Blurred Vision
- Urinary Retention
- Sexual Dysfunction
How to Store AMITONE 25MG TABLET 10'S
- Store amitriptyline at room temperature, typically between 20°C to 25°C (68°F to 77°F).
- Keep AMITONE 25MG TABLET 10'S in its original packaging or container, tightly closed.
Frequently asked questions about AMITONE 25MG TABLET 10'S
AMITONE 25MG TABLET 10'S is used to treat conditions such as major depressive disorder, chronic pain, migraines, and certain sleep disorders.
AMITONE 25MG TABLET 10'S works by affecting the levels of neurotransmitters, specifically serotonin and Norepinephrine, in the brain. It inhibits their reuptake, leading to increased concentration and improved mood.
It may take several weeks for the full therapeutic effects of AMITONE 25MG TABLET 10'S to be noticeable. Individual response times may vary.
Yes, AMITONE 25MG TABLET 10'S is often prescribed for chronic pain conditions such as neuropathic pain, fibromyalgia, and certain headaches.
Yes, weight gain is a potential side effect of AMITONE 25MG TABLET 10'S.
AMITONE 25MG TABLET 10'S is generally not recommended for use in children, as its safety and effectiveness in this age group have not been well-established.
AMITONE 25MG TABLET 10'S can be taken with or without food, as directed by your healthcare provider.
The duration of AMITONE 25MG TABLET 10'S treatment will be determined by your healthcare provider. It is important to follow their instructions and not discontinue the medication without consulting them.
If you miss a dose of AMITONE 25MG TABLET 10'S, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and resume your regular dosing schedule.
References related to AMITONE 25MG TABLET 10'S
- Amitriptyline. Princeton: Sandoz Inc; 2014. [Accessed on 19 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Amitriptyline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
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